Can I use Nginx?

Yes, Bugify should run fine on Nginx. Below is an example config file that you might want to use when running Bugify on Nginx.

server {
    listen 80;
    server_name bugify.example.com;
    root /var/www/bugify.example.com/public;
    index index.php;

    location / {
      # Send all requests for non-static content to index.php
      try_files $uri $uri/ /index.php?$query_string;

      fastcgi_param QUERY_STRING $query_string;
    }

    location ~ \.php$ {
      fastcgi_pass   unix:/var/run/php-fastcgi/php-fastcgi.socket;
      fastcgi_index  index.php;
      fastcgi_param  SCRIPT_FILENAME /var/www/bugify.example.com/public$fastcgi_script_name;
      include        fastcgi_params;
    }
}

Please note that some people have found the following works better for them:

location / { 
    # Send all requests for non-static content to index.php 
    if (!-e $request_filename) { 
        rewrite ^/(.*)$ /index.php?q=$1 last; 
        break; 
    }

    fastcgi_param QUERY_STRING $query_string; 
}